ABSTRACT
To study the usefulness of JPEG2000 compression for nuclear medicine (NM) image, normal and abnormal static images were compressed using a JPEG2000 plug-in. For lossless algorithm, the compressing ratio (CR) was calculated. For lossy algorithm, images were visually analyzed by NM physicians and ROC curves were generated. The area under ROC curve (AUC) was used as the index of image diagnostic quality. Paired sample t tests were performed to compare the AUCs. It was found that the lossless CR was (1.34+/-0.05) : 1. For lossy algorithm, the AUC decreased with the increase of CR. Comparison between the original and the compressed images revealed no significant difference for 10:1 CR but significant difference for bigger CRs. It was concluded that lossless compression has little usefulness for NM image because of very low CR. While lossy compression isused, the diagnostic quality of static NM images is preserved at CRs 50 : 1,40 : 1, 30 : 1,20 : 1 up to 10 : 1. For other types of NM image, CR should be increased or decreased according to their characteristics, especially the level of intrinsic statistical noise of NM image.
Subject(s)
Humans , Algorithms , Area Under Curve , Artifacts , Data Compression , Methods , Reference Standards , Image Processing, Computer-Assisted , Nuclear Medicine , Methods , Radionuclide Imaging , Thyroid Gland , Diagnostic ImagingABSTRACT
Performance of the electrochemiluminescent immunoassay system of Elecsys 2010 was evaluated by quantitative assay. The functional sensitivity of the TSH assay was 0.004 microU/ml. The extra-assay imprecision was RSD = 1.45%-4.65% in the range of TSH concentrations of 0.43-88.15 microU/ml. The intra-assay imprecision was RSD = 1.38%-3.14% in the range of TSH concentrations of 0.41-87.28 microU/ml. The recovery of TSH was in the range of 98.6%-104.4%. The correlation between theoretical values and obtained values of TSH was adequate(r = 0.999). We conclude that the Elecsys 2010 is provably satisfactory in sensitivity, precision, accuracy, reliability, practicability and rapidity.
Subject(s)
Humans , Electrochemistry , Evaluation Studies as Topic , Immunoassay , Reference Standards , Luminescent Measurements , Sensitivity and Specificity , Thyrotropin , BloodABSTRACT
Objective:To improve the dual plate testing,using mono plate reagent kits of thyroid humor items by re programming for 1235 AutoDelfa and potimize test time of dual plate by presetting the testing priority.Methods:The possibility of dual plate testing using mono plate reagent kits was evaluated,by comparative study of the volume of each reagent bottle located in the kits and the volume of each reagent used in clinical experiment of dual plate testing for 5 thyroid hormone items.All the new control files and assay files of thyroid hormone items for dual plate were created by reprogramming.The experiment time for dual plate testing was decreased by presetting the testing priority.Results:The maximum samples per test were increased from 96 to 192 for thyroid hormone test.The time for dual plate test was decreased from 8 hours to 6 hours.Conclusion:The clinical performance of the developed way was successful.The clinical performance of 1235 AutoDelfia could be developed by the application of this study.